أثر خلات الرصاص وفيتامين جـ على بعض القياسات الكيموحيوية لكلى طائر السمان المحلي

Abstract

The present study, focused on effects of sub-lethal dose of lead acetate 600 ppm and ascorbic acid 60 mg/kg of local quail (Coturnix sp) on uric acid, blood urea and creatinine. Forty healthy birds were divided into four groups (six birds each) and one group was kept as un-medicated control (A). Group B and C were medicated with ascorbic acid (60 mg/kg of body weight) and lead acetate (600 ppm) in a single dose respectively. Group D was medicated with lea acetate for ten days, then given ascorbic acid for remaining 11 days. Biochemical parameters were determined by using spectrophotometer (Cobas integra 400).

Results showed that, increase was recorded in uric acid, urea and creatinine levels in all medicated groups. Uric acid, urea and creatinine levels were significantly (P<0.05) higher in groups medicated with high doses of 240 and 280 mg/kg b.wt of lead acetate. Furthermore, vitamins C in lead acetate intoxicated birds showed some ameliorative effects to Pb toxicity. It was concluded that the vitamin C can ameliorate the toxic effects of Pb poisoning in quails at higher dose rate.