Preparation and Antifungal Study of Some Ammonium Salts Derived from Acetic Acid and Trichloroacetic Acid

Abstract

This work is concerned with the preparation of a number of organic ammonium acetate and trichloroacetate salts (ionic liquids; ILs) throughout a reaction of the acetic acid and trichloroacetic acid with some aliphatic and aromatic amines including the ammonia. Ten organic ammonium carboxylate salts were obtained, some of them were in the form of solid salts, whereas others were as liquids (ionic liquids; ILs) at room temperature. The yields of the resulting organic salts ranged from (21%) to (79%). However, some attempts towards the preparation of other organic salts were not successful. The obtained organic ammonium carboxylate salts/ionic liquids were characterized using spectroscopic techniques such as the infrared (IR), the nuclear magnetic resonance spectroscopy (1HNMR) and the mass spectrometry (ms). The antifungal properties of these organic ammonium carboxylate salts were studied against the aspergillus niger (A. niger). The antifungal results were compared with the daktarin (a commercially available antifungal agent), which was used as a reference.