Synthesis of Some Benzyl Oxime Ethers

Abstract

A reaction between hydroxylamine hydrochloride with five aldehydes and ketones under basic conditions produced oximes 1 – 5 in moderate to excellent yields. These five resulting oximes were characterized using spectroscopic techniques, including IR, ¹HNMR and mass spectrometry. The obtained analytical data confirmed the structures of all five oximes. The ¹HNMR of the acetaldehyde oxime 1 showed the formation of two geometrical isomers in a ratio of (1:1) These oximes were then subjected into a reaction with the benzyl chloride mild basic conditions by which the corresponding benzyl oxime ethers 6 – 10 were obtained in moderate to
excellent yields ranging from 37% to 95%.